Organic Schisandra Berry (50 Grams)

Longevity • Stress • Balance*

$29.99

Units Sold: 17,313

Schisandra is the adaptogenic “all-systems” berry, making it an ultimate all-in-one tonic.* It supports stress resilience and endurance while promoting calm focus and mental clarity under pressure.* Schisandra also supports the liver, mitochondria, skin health, and the gut.* There’s not a part of the body that it doesn’t help.* We proudly offer high-quality organic Schisandra chinensis berry powder.

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Schisandra: The Adaptogenic “All-Systems” Berry*

Clinically-Studied “Five-Flavor Fruit” with a 40+ Year Russian Research Legacy, that Supports Energy, Cognition, the Liver, Immunity, Metabolism, Hormones, and Even More*

Fresh goji berries and schisandra berries on a branch, herbal supplement ingredients.

There are herbs that soothe. Herbs that stimulate. Herbs that target one organ. Schisandra is different. It’s a berry with a range that touches on virtually every part of the body. It’s a complete formula unto itself.

That’s why it shows up again and again in both traditional use and modern research. Traditional herbalism revered its wide range of effects. Russian researchers made it official, with Schisandra being one of the herbs that the term “adaptogen” was coined for. Modern research in the West is just starting to scratch its multifaceted surfaces across a range of human trials.

The Ancient Lore of Schisandra

The Divine Farmer’s Classic of the Materia Medica (Shen Nong Ben Cao Jing) lists Schisandra as among the superior herbs, saying that it would “prolong the years of life without aging.”*

Often also spelled schizandra and known in China as Wu Wei Zi, it is known as a top herb to support healthy aging in Chinese medicine, Schisandra chinensis is said to enter into every meridian channel in the body, once again a quite unique claim to fame.*

It works on the five elements: water, wood, fire, earth, and metal, supporting a wide range of the body’s systems, though is most known for supporting the liver, brain, kidneys, and lungs.*

And it contains all three treasures; Jing, Qi, and Shen, making this one herb a formula unto itself.*

Fresh Schisandra berries with powder and extract for health benefits.

Adaptogen – Your “Schisandra Stress Shield”*

Adaptogens’ job isn’t to force you up or down, it’s to help your body normalize under stress and protect your performance when life applies pressure.

In the research literature, the stress-protective effect of adaptogens is tied to regulation of homeostasis, especially through pathways connected to the hypothalamic-pituitary-adrenal (HPA) axis, the master system that sets your stress rhythm, energy output, and recovery signals.*¹

What this means to you is more capacity. More stability. Better output with less breakdown. And it’s nothing like caffeine or other stimulants with the classic liabilities, including tolerance, rebound, sleep disruption, or that “comedown” feeling.

A wide range of Russian research showed increased endurance and mental performance in people with reductions in fatigue over taking Schisandra for 2 to 10 weeks.*^1-3
Even a single dose of Schisandra supported mental performance and physical working capacity in humans.*⁴
Schisandra has long been noted for supporting the body’s natural resilience to a wide range of physical and environmental stressors, including: heat shock, burns, extreme cold, immobilization, heavy exertion under load, low-pressure environments, inflammation, irradiation, and heavy metal intoxication.*³
In two different trials with older adults (50+), 12 weeks of Schisandra extract was associated with better knee extensor or quadricep strength versus placebo, showing real world effects in physical training.*^5,6

To put it in other terms, Schisandra supports your body and mind to build resilience.* Schisandra’s adaptogenic profile is strongly linked to its lignan complex (with schisandrin/schisandrin B among the major compounds). These and other compounds help support:

HPA axis modulation and stress mediator regulation*^1,2
Antioxidant and healthy inflammation modulation*^1,2
Reported changes in cortisol baseline levels*^1,2

Schisandra’s Nootropic Effects*

I can personally feel the effects of Schisandra right away, in how it sharpens the mind.* Pop some powder in my mouth, and it’s like the mind tightens up with the mostly sour and astringent taste.*

Schisandra’s lignans aren’t locked out of the brain. In animal research, schisandrin B (one of the most abundant lignans) has been shown to cross the blood–brain barrier, which helps explain why Schisandra is repeatedly studied for its support of cognition.⁷ Some of its effects include:

Oxidative stress buffering (brain tissue is oxidation-sensitive)*^8,9
Supporting healthy neuroinflammation*^8,9
Supporting neuroprotection*^8,9
Supporting neurotransmitter and BDNF-related pathway modulation*^8,9

One of the most compelling angles is that Schisandra doesn’t only act “top-down” through the brain, it also supports “bottom-up” via the gut, helping to shape the gut-brain axis.*⁷ The gut effects covered later matter for your brain too.

Schisandra Supports the Liver, including Phase I and II Detoxification*

Schisandra’s lignans have been observed to interact with the same enzyme networks the liver uses to transform and clear compounds from the body.*¹⁰

Phase I (activation/transformation): Schisandra lignans can support the activity of cytochrome P450 pathways (notably CYP3A4/CYP2C9).*¹⁰
Phase II (conjugation/neutralization): Multiple lignans, such as Schizandrin C, have been shown to support antioxidants such as glutathione.*¹⁰

To put it simply, Schisandra supports the liver’s ability to process and neutralize chemical toxins efficiently.¹⁰

Meanwhile, it also helps to protect liver tissue under oxidative or inflammatory stress.* A systematic review of animal studies found Schisandra compounds were associated with significant improvements in liver stress markers.*¹¹

Why Schisandra Feels Like Clean Power – Mitochondrial Capacity and Effects on Metabolism*

Mitochondria are the powerhouses of your cells, yet for many people, they’re falling behind. A mitochondria-focused review describes Schisandra fruits/extracts and their constituents as helping restore impaired mitochondrial function, acting as mitoprotective agents.*¹²

This matters for real people, too. In a 12-week randomized, double-blind, placebo-controlled clinical trial in people taking Schisandra, the group showed improvements across multiple metabolic markers, including healthy glucose and normal insulin levels.*¹³

Schisandra can help deliver more mitochondrial and metabolic steadiness with less energy volatility.*

Immunomodulation Through the Gut*

Schisandra supports immune regulation, and a big part of that happens through the gut ecosystem, where much of immune signaling is trained.*

In a 12-week double-blind, placebo-controlled trial in women, Schisandra supplementation was associated with changes in gut microbiota, with notable correlations between specific bacteria and fat mass.*¹⁴

Other research has shown that Schisandra can increase beneficial genera like Akkermansia and Bifidobacterium, which are commonly associated with healthier gut-barrier and inflammatory signaling.*¹⁵

These matter not just for your gut or your immune system. They matter for your brain too. Work on the microbiota–gut–brain axis suggests Schisandra extracts, when they shift microbiota, can increase short-chain fatty acids (like butyrate/propionate).*⁷

Hormonal & Menopausal Support*

In a randomized, double-blind, placebo-controlled clinical trial evaluating Schisandra extract for menopausal symptoms, the Schisandra group showed favorable changes in total symptom scores, with particular benefits noted for symptoms like hot flushes, sweating, and heart palpitations.*¹⁶

All of this is done through the various effects mentioned above. And while it is only from rat research, there is the intriguing idea that Schisandra could help modulate the hormone prolactin.*¹⁷ This hormone can creep too high in both men and women, which can cause issues with testosterone and progesterone.*

Shen, Skin, Anti-Aging and Beauty-From-Within*

It’s interesting that herbs that help support Shen, that is, the spirit and mind, tend to also be herbs that help support beauty.* It’s like that inner beauty is reflected outwards.

Schisandra has long been renowned in China, especially by women, for its role in supporting radiant aging and beauty benefits, specifically, for improving skin condition.* It can be used both internally and externally for these purposes.

This appears to be primarily due to its antioxidant and inflammation-modulating properties.*¹⁸

The gut and liver are a huge part of detox. Toxins are released and eliminated through the skin. Therefore, when the liver is functioning properly, the skin will naturally clear up.

Our Schisandra Quality

Unfortunately, the USA-grown Schisandra is no longer available. Everyone who took it loved this amazing Schisandra, but unfortunately, with the death of the man who started it, the farm was ultimately destroyed.

The good news is we think we’ve found the next best thing to take its place.

Most of the Schisandra berries and powders available on the market are heavily oxidized. This is because the berries do not handle transportation and storage so well in their raw state. While it may still be good, it doesn’t contain all the power that fresh Schisandra berries can deliver.

This is organic Schisandra chinensis, grown in China. While there are other species sometimes available (such as Schisandra sphenanthera), ours is the primary species that is used and studied. After harvesting, the berries are dried and ground up. This powder delivers the full spectrum of nutrients found in the berries, including the seeds.

As with all our herbs, it passes independent lab testing with flying colors.

Dosing and How to Take

Recommended starting dose is ¼ to ½ tsp daily. (This is approximately 1.8 to 3.5 grams. At this dose, each 50-gram bag will last about 2 to 4 weeks.)

Try taking Schisandra straight, stirring it into hot water for tea, or mixing it into various shakes or smoothies.

Watch out for oxidation. Please keep your Schisandra in the package and away from air, light, and heat as much as possible to preserve its freshness.

Organic Schisandra berry powder in a wooden spoon, herbal supplement for energy.

Take the 100 Day Schisandra Challenge

Ron Teeguarden, a premiere tonic herbalist in the West, said that when he first was introduced to the herbs, his teacher told him to take Schisandra for 100 days straight without fail to transform his life. Schizandra was also the favorite herb of this teacher, Taoist Grand Master Sung Jin Park.

Simply take X teaspoon (approximately X gram) mixed in water or other liquids for 100 days and enjoy all the many wonderful benefits of this single herb. (Note: It doesn’t require 100 days of consumption to feel the benefits.)

Schisandra Berry Tea and Iced Fruit Drink

Contraindications and Side Effects

Schisandra is generally described in all the research as well-tolerated and not associated with serious side effects when used appropriately.

Schisandra can be stimulating, so it is best not taken before bed. Mornings and afternoons work for most.

Schisandra should not be used while pregnant, as historically it was used to induce labor. It is also not recommended to use while breastfeeding.

While Schisandra helps to support the immune system, classically, it is recommended to avoid taking Schisandra when you have a common cold or flu because it has astringent properties that can hold moisture in the body.*

Schisandra can be combined with any other herbs.

Organic Schisandra berry powder for health and vitality, 50g.

Schisandra berry powder supplement for liver health, stamina, and mental clarity. Supports stress re.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

WARNING: Consuming this product can expose you to chemicals including Lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.

For more information on what this warning is, visit https://lostempireherbs.com/california-prop-65

Additional information

Weight	3.2 oz
Dimensions	5 × .5 × 8 in
Dosage	Take 1 tsp once or twice daily.
Size & Servings	50 Grams
Product Of	China
Type	Powder
Dietary	Gluten Free, Paleo Friendly, Vegan Friendly
Does Not Contain	GMO's, Fillers, Preservatives, Added Sugar, Artificial Flavorings or Colorings

References

Panossian, A., & Wikman, G. (2010). Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity. Pharmaceuticals (Basel, Switzerland), 3(1), 188–224. https://doi.org/10.3390/ph3010188
Panossian, A., & Wikman, G. (2009). Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Current clinical pharmacology, 4(3), 198–219. https://doi.org/10.2174/157488409789375311
Panossian, A., & Wikman, G. (2008). Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine. Journal of ethnopharmacology, 118(2), 183–212. https://doi.org/10.1016/j.jep.2008.04.020
Panossian, A., & Wagner, H. (2005). Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration. Phytotherapy research : PTR, 19(10), 819–838. https://doi.org/10.1002/ptr.1751
Park, J., Han, S., & Park, H. (2020). Effect of Schisandra Chinensis Extract Supplementation on Quadriceps Muscle Strength and Fatigue in Adult Women: A Randomized, Double-Blind, Placebo-Controlled Trial. International journal of environmental research and public health, 17(7), 2475. https://doi.org/10.3390/ijerph17072475
Cho, Y. H., Lee, S. Y., Lee, C.-H., Park, J.-H., & So, Y. S. (2021). Effect of Schisandra chinensis Baillon extracts and regular low-intensity exercise on muscle strength and mass in older adults: A randomized, double-blind, placebo-controlled trial. The American Journal of Clinical Nutrition, 113(6), 1440–1446. https://doi.org/10.1093/ajcn/nqaa447
Pferschy-Wenzig, E. M., Pausan, M. R., Ardjomand-Woelkart, K., Röck, S., Ammar, R. M., Kelber, O., Moissl-Eichinger, C., & Bauer, R. (2022). Medicinal Plants and Their Impact on the Gut Microbiome in Mental Health: A Systematic Review. Nutrients, 14(10), 2111. https://doi.org/10.3390/nu14102111
Sowndhararajan, K., Deepa, P., Kim, M., Park, S. J., & Kim, S. (2018). An overview of neuroprotective and cognitive enhancement properties of lignans from Schisandra chinensis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 97, 958–968. https://doi.org/10.1016/j.biopha.2017.10.145
Zhang, M., Xu, L., & Yang, H. (2018). Schisandra chinensis Fructus and Its Active Ingredients as Promising Resources for the Treatment of Neurological Diseases. International journal of molecular sciences, 19(7), 1970. https://doi.org/10.3390/ijms19071970
Addissouky TA, El Sayed IET, Ali MMA, Alubiady MHS, Wang Y. Schisandra chinensis in Liver Disease: Exploring the Mechanisms and Therapeutic Promise of an Ancient Chinese Botanical. Arch Pharmacol Ther. 2024;6(1):27-33. https://www.scientificarchives.com/article/schisandra-chinensis-in-liver-disease-exploring-the-mechanisms-and-therapeutic-promise-of-an-ancient-chinese-botanical
Huang, B. H., Lv, B. H., Wu, D. J., Xiong, F. Y., Li, Y. B., Lu, Y. P., & Lv, W. L. (2025). Efficacy of Schisandra chinensis in liver injury: a systematic review and preclinical meta-analysis. Frontiers in pharmacology, 16, 1627081. https://doi.org/10.3389/fphar.2025.1627081
Kopustinskiene, D. M., & Bernatoniene, J. (2021). Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents. Antioxidants (Basel, Switzerland), 10(4), 620. https://doi.org/10.3390/antiox10040620
Kim, D. S., Baek, H. I., Ha, K. C., Cha, Y. S., & Park, S. J. (2022). Efficacy and Safety of Omija (Schisandra chinensis) Extract Mixture on the Improvement of Hyperglycemia: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial. Nutrients, 14(15), 3159. https://doi.org/10.3390/nu14153159
Song, M. Y., Wang, J. H., Eom, T., & Kim, H. (2015). Schisandra chinensis fruit modulates the gut microbiota composition in association with metabolic markers in obese women: a randomized, double-blind placebo-controlled study. Nutrition research (New York, N.Y.), 35(8), 655–663. https://doi.org/10.1016/j.nutres.2015.05.001
Huang, M., Cople-Rodrigues, C. D. S., Waitzberg, D. L., Rocha, I. M. G. D., & Curioni, C. C. (2023). Changes in the Gut Microbiota after the Use of Herbal Medicines in Overweight and Obese Individuals: A Systematic Review. Nutrients, 15(9), 2203. https://doi.org/10.3390/nu15092203
Park, J. Y., & Kim, K. H. (2016). A randomized, double-blind, placebo-controlled trial of Schisandra chinensis for menopausal symptoms. Climacteric : the journal of the International Menopause Society, 19(6), 574–580. https://doi.org/10.1080/13697137.2016.1238453
Hong, S., Li, M., Jeung, E., Lee, G., Hong, E., Choi, Y., & An, B. (2017). Therapeutic effects of Schisandra chinensis on the hyperprolactinemia in rat. International Journal of Oncology, 50, 1448-1454. https://doi.org/10.3892/ijo.2017.3881
Nowak, A., Zakłos-Szyda, M., Błasiak, J., Nowak, A., Zhang, Z., & Zhang, B. (2019). Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives. Nutrients, 11(2), 333. https://doi.org/10.3390/nu11020333

Lab Results

Heavy Metals details for Schisandra shown below. For more on our Heavy Metal Grading System go here.

Heavy Metals	Arsenic	Cadmium	Lead	Mercury	Average Grade/Max Dosage
Test Results (ppm)	0.115	0.003	0.236	0.002
Max Dose Levels (mcg)	0.46	0.012	0.944	0.08	4g / 2 tsps
Max Dose Levels (mcg)

FAQ

Details about Schisandra:

What is Schisandra?

Schisandra chinensis It is an adaptogenic berry used for centuries in Traditional Chinese Medicine and later studied extensively in Russian research. It is often described as a formula unto itself because it can support multiple systems at once, including stress resilience, cognition, liver capacity, immune balance through the gut, and metabolic steadiness.

What other names does it go by?

Schisandra is also known as Wu Wei Zi, which means five flavor fruit, and it is sometimes spelled Schizandra. You may also see it referred to as magnolia vine berry in some English herb sources.

What is it used for?

Schisandra is most commonly used to support stress resilience and endurance, calm focus and mental performance under pressure, liver resilience and antioxidant defenses, immune balance, including gut ecology, skin health, and supporting metabolism.

What does Schisandra tastes like?

Schisandra is known as the five flavor fruit, but most people notice sour and astringent first, especially in powder form. The flavor also includes subtler flavors of bitter, pungent, salty, and sweet notes.

Are Schisandra chinensis and Schisandra sphenanthera equivalent?

They are not equivalent. Both species have a history of use, but Schisandra chinensis is the classic Wu Wei Zi species and is the primary species most commonly referenced across much of the modern research. This is why we use Schisandra chinensis for our product.

Quality:

Is this organic?

Yes, this is an organic Schisandra product.

Where does your powder come from?

Our Schisandra powder is sourced from organic Schisandra grown in China, which is the traditional region for this herb and the primary species used and studied. We chose this source because the species identity and quality are consistent with the research and traditional use.

How is it processed?

After harvesting, the berries are dried and then ground into a powder. The powder is made from the whole berry, including the seeds, which helps preserve a broad spectrum profile rather than relying on a narrow isolated fraction.

What are the active constituents?

Schisandra is a complex botanical, but the most highlighted actives include lignans such as schisandrin and schisandrin B, along with polysaccharides, essential oils, and flavonoids. This multi-constituent profile is a big reason Schisandra can feel like a full formula rather than a single-note supplement.

Are Schisandra leaves and stems usable?

In some traditional contexts, other parts of the plant may be used, and some analyses suggest leaves can contain beneficial compounds. However, the fruit is the primary traditional and research-focused part of the plant, and that is why we use the berries.

How to Take Schisandra:

How to take Schisandra?

Start with a small amount and assess your response. A common starting approach is one-half teaspoon once daily, then increasing to one teaspoon once or twice daily as desired. It can be consumed straight or added to liquid.

When to take Schisandra?

While it has no caffeine, many people do find it stimulating, so it is not recommended before bed. Many people prefer taking it earlier in the day, either in the mornings or afternoon.

How to make Schisandra tea?

Add the powder to hot water and stir, then let it steep for a few minutes. It will not dissolve completely, so think of it as a rustic berry tea. You can simmer it gently for a stronger cup, and you can add honey, lemon, or ginger if you want to round out the sour and astringent taste.

How to make Schisandra tincture?

You can make a tincture from our Schisandra using alcohol. If you want a simple, reliable home method, macerate the berry powder in at least 80-proof alcohol in a sealed jar for several weeks, shake daily, then strain.

How else can I use this?

Schisandra powder can be mixed into smoothies, shakes, oatmeal, yogurt, or applesauce. Use your imagination.

Should I take Schisandra with food?

Either can work. If you have a sensitive stomach, take it with food, and if you want a quicker taste-linked effect, you can take a small amount with water.

Do I need to cycle Schisandra?

No. Most people take Schisandra continuously because it is often used as a capacity-building tonic.

Can I take it with coffee?

Yes, many people enjoy combining Schisandra with coffee. Some find it helps the energy feel steadier and cleaner, although the flavors do contradict each other.

What is the best way to store the powder?

Store Schisandra sealed and away from air, heat, and light. Oxidation can dull flavor and reduce potency over time, so keep the package closed and avoid storing it near heat sources.

Effects:

Is it a stimulant?

Schisandra is not a stimulant in the caffeine sense. It is best understood as an adaptogen that supports performance and resilience under stress without the classic stimulant liabilities like crashiness and tolerance. Some people do experience it as mildly energizing or focusing, so if you are sensitive, start low and avoid taking it late in the day.

Is it good for the liver?

Schisandra is one of the most research-highlighted herbs for liver support. It is often discussed for supporting antioxidant defenses and healthy inflammation modulation in the liver, and for supporting the liver’s processing pathways.

Is it good for anxiety?

Schisandra is not primarily a sedative, but many people experience it as calm focus and increased steadiness under stress. If your anxious feeling is tied to nervous system fatigue and a dysregulated stress response, Schisandra may be supportive. If you need strong calming effects at night, you may prefer pairing it with dedicated calming herbs.

Is it good against depression?

Schisandra is not intended for depression. It has been studied for neuroprotective effects and for mechanisms related to oxidative stress and healthy inflammation modulation, and there is also preclinical interest in gut-brain axis pathways.

When will it start to work?

Some people notice effects the first day, especially a sense of clarity or steadier energy. For deeper adaptogenic benefits like endurance, resilience, and more stable recovery, many people notice the strongest changes after consistent use over several weeks.

Side Effects and Contraindications:

Is Schisandra safe during pregnancy?

Schisandra is generally not recommended during pregnancy unless you are working with a qualified practitioner. Traditional sources include uses related to labor, so it is best to be conservative.

Are there any safety issues?

Schisandra is generally well tolerated when used appropriately, but caution matters if you are pregnant, breastfeeding, or taking prescription medications. Because Schisandra can influence liver enzyme pathways involved in metabolizing many compounds, it may affect how certain medications are processed, so consult a clinician or pharmacist if you take prescriptions.

Why shouldn’t you take it during colds?

In traditional herbal frameworks, Schisandra is considered astringent and consolidating, so some practitioners avoid it during the early phase of an acute cold or flu when the strategy is often to release rather than hold. This is a traditional guideline, not a modern medical directive, so if you are unsure, consult a qualified practitioner.

Combinations with Other Herbs:

Can I mix it with something to use it on my skin?

Yes, you can combine Schisandra powder with gentle carriers like honey, aloe gel, or a simple oil such as jojoba to create a topical application. Always patch test first to check sensitivity, and remember that internal support for oxidative stress and inflammatory tone often has the biggest influence on skin resilience.

Can I mix it with any other herbs?

Schisandra pairs well with many herbs. Many people combine it with other adaptogens for performance, like in our Spartan Formula or Athena Formula.

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