Lion’s Mane – The Mushroom for the Brain

Hericium erinaceus (popularly known as Lion’s Mane, due to its appearance) is a type of edible mushroom found on hardwoods in North America, Asia and Europe.

This mushroom has astounding mental regenerative abilities, unlike any other mushroom. This makes it a potent nootropic for the enhancement of the mind.

It possesses the ability to stimulate the growth of neurons in the astrocytes by increasing NGF mRNA expression. In one study in particular, it found in mice that the hippocampus (our main long-term memory storehouse) was particularly influenced ⁽¹⁾.*

It appears as cascading hairs on a ball-like hard core, much like the back of a Lion’s head. It has long been used in traditional Chinese medicine for immunity and to improve digestion.

Lion’s Mane Mushroom and the Brain

• • • Nerve Growth Factors (NGF), i.e. stimulates the growth of neurons ^{(1)(2)(4)(5)*}
    • Helps repair the brain from physical damage ^(3)(5)(6)*
    • Helps prevent or slow age-related mental degradation^(5)*
    • Has mood regulating effects from the NGF and other non-NGF factors ^(4)*
    • Has been shown to increase ‘curiosity’ of objects in the world in animal studies*

Really important to realize is that the effects of this nootropic herb have been found to level off particularly fast after use is stopped (around 2-4 weeks) ⁽¹⁾.*

To gain the potential benefits, it is therefore recommended that consumption of Lion’s Mane takes place every day. The culinary use of Lion’s Mane by the Chinese shows that this is a safe habit to practice.

And Many More Benefits

But this mushroom isn’t just good for the mind. Consumption of this mushroom, whether in whole form or as an extract, has been shown to potentially provide the following benefits.

• • • Promotes cellular apoptosis ^{(4)(7)(8)(9)(10)*}
    • Provides a cascade of nutrients ^{(11)(12)(13)*}
    • Anti-fatigue properties ^(14)*
    • High antioxidant containing as all mushrooms are ^(13)*
    • 20% protein by volume
    • Wound healing abilities when applied topically ^(12)(15)*
    • Gastrointestinal protective effects ^(4)(16)(17)*
    • Anti-inflammatory ^(5)(18)*

Organic Lion’s Mane 1:1 Water Extract

Our Lion’s Mane is a 1:1 water extraction of real lion’s mane mushrooms, grown on wood in greenhouses with natural light, fresh air and using organic methods.

Compliments of North American Reishi/Nammex

Our lion’s mane is NOT a mycelium grown on grain substrate. It is guaranteed to have at least 25% beta glucans.

Recommended dosage is 2-5 grams per day. This is approximately ½ teaspoon to 1 tsp twice daily. As a mushroom it is safe to use even in higher doses too.

Additional information

References

1. Nerve Growth Factor-Inducing Activity of Hericium erinaceus in 1321N1 Human Astrocytoma Cells
   Koichiro Mori – Yutaro Obara – Mitsuru Hirota – Yoshihito Azumi – Satomi Kinugasa – Satoshi Inatomi – Norimichi Nakahata – Biol. Pharm. Bull. Biological & Pharmaceutical Bulletin – 2008
2. Neurotrophic Properties of the Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia 
   Puei-Lene Lai – Murali Naidu – Vikineswary Sabaratnam – Kah-Hui Wong – Rosie David – Umah Kuppusamy – Noorlidah Abdullah – Sri Malek – International Journal of Medicinal Mushrooms Int J Med Mushr – 2013
3. Neuroregenerative Potential of Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Higher Basidiomycetes), in the Treatment of Peripheral Nerve Injury (Review) 
   Kah-Hui Wong – Murali Naidu – Rosie David – Robiah Bakar – Vikineswary Sabaratnam – International Journal of Medicinal Mushrooms Int J Med Mushr – 2012
4. Hericium erinaceus (Yamabushitake): a unique resource for developing functional foods and medicine.
   Mingxing Wang – Yang Gao – Duoduo Xu – Tetsuya Konishi – Qipin Gao – Food Funct. – 2014
5. Protective Effects of Hericium erinaceus Mycelium and Its Isolated Erinacine A against Ischemia-Injury-Induced Neuronal Cell Death via the Inhibition of iNOS/p38 MAPK and Nitrotyrosine 
   Kam-Fai Lee – Jiann-Hwa Chen – Chih-Chuan Teng – Chien-Heng Shen – Meng-Chiao Hsieh – Chien-Chang Lu – Ko-Chao Lee – Li-Ya Lee – Wan-Ping Chen – Chin-Chu Chen – Wen-Shih Huang – Hsing-Chun Kuo – IJMS International Journal of Molecular Sciences – 2014
6. Hericium erinaceus (Bull.: Fr.) Pers., a medicinal mushroom, activates peripheral nerve regeneration 
   Kah-Hui Wong – Gowri Kanagasabapathy – Murali Naidu – Pamela David – Vikineswary Sabaratnam – Chinese Journal of Integrative Medicine Chin. J. Integr. Med. – 2014
7. Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells
   Sung Kim – Mi Kang – Yong Choi – Jae Kim – Seok Nam – Mendel Friedman – Food & Function Food Funct. – 2011
8. Isolation and identification of aromatic compounds in Lion’s Mane Mushroom and their anticancer activities 
   Wei Li – Wei Zhou – Eun-Ji Kim – Sang Shim – Hee Kang – Young Kim – Food Chemistry – 2015
9. Hericium erinaceus (Lion’s Mane) Mushroom Extracts Inhibit Metastasis of Cancer Cells to the Lung in CT-26 Colon Cancer-Tansplanted Mice
   Sung Kim – Seok Nam – Mendel Friedman – J. Agric. Food Chem. Journal of Agricultural and Food Chemistry – 2013
10. Effect of the replacement of aspartic acid/glutamic acid residues with asparagine/glutamine residues in RNase He1 from Hericium erinaceus on inhibition of human leukemia cell line proliferation
    Hiroko Kobayashi – Naomi Motoyoshi – Tadashi Itagaki – Mamoru Suzuki – Norio Inokuchi – Bioscience, Biotechnology, and Biochemistry – 2014
11. Vitamin B 12 [ c -lactone], a Biologically Inactive Corrinoid Compound, Occurs in Cultured and Dried Lion’s Mane Mushroom ( Hericium erinaceus ) Fruiting Bodies
    Fei Teng – Tomohiro Bito – Shigeo Takenaka – Yukinori Yabuta – Fumio Watanabe – J. Agric. Food Chem. Journal of Agricultural and Food Chemistry – 2014
12. Hericium erinaceus: an edible mushroom with medicinal values 
    Md. Khan – Mousumi Tania – Rui Liu – Mohammad Rahman – Journal of Complementary and Integrative Medicine – 2013
13. Composition and antioxidant activity of water-soluble oligosaccharides from Hericium�erinaceus 
    Yiling Hou – Xiang Ding – Wanru Hou – Molecular Medicine Reports Mol Med Report – 2014
14. Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus 
    Jianqing Liu – Congxin Du – Yifei Wang – Zhihua Yu – Experimental and Therapeutic Medicine Exp Ther Med – 2014
15. Potential Activity of Aqueous Extract of Culinary-Medicinal Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Aphyllophoromycetideae) in Accelerating Wound Healing in Rats 
    Mahmood Abdulla – Atieh Fard – Vikineswary Sabaratnam – Kah-Hui Wong – Umah Kuppusamy – Noorlidah Abdullah – Salmah Ismail – International Journal of Medicinal Mushrooms Int J Med Mushr – 2011
16. In Vitro Anti-Helicobacter pylori Effects of Medicinal Mushroom Extracts, with Special Emphasis on the Lion’s Mane Mushroom, Hericium erinaceus (Higher Basidiomycetes)
    Xiaodong Shang – Qi Tan – Ruina Liu – Kangying Yu – Pingzuo Li – Guo-Ping Zhao – International Journal of Medicinal Mushrooms Int J Med Mushr – 2013
17. Gastroprotective Effects of Lion’s Mane Mushroom Hericium erinaceus (Bull.:Fr.) Pers. (Aphyllophoromycetideae) Extract against Ethanol-Induced Ulcer in Rats 
    Jing-Yang Wong – Mahmood Abdulla – Jegadeesh Raman – Chia-Wei Phan – Umah Kuppusamy – Shahram Golbabapour – Vikineswary Sabaratnam – Evidence-Based Complementary and Alternative Medicine – 2013
18. Anti-inflammatory Activity of Mycelial Extracts from Medicinal Mushrooms 
    Yan Geng – Shuiling Zhu – Zhenming Lu – Hongyu Xu – Jin-Song Shi – Zheng-Hong Xu – International Journal of Medicinal Mushrooms Int J Med Mushrooms – 2014

Lab Results

1. Certificate of Analysis
2. Complete Mineral and Heavy Metals Report
3. Microbiology Report